4quick sleep mceODT

Melatonin primarily responsible for regulating body’s circadian rhythm to manage natural sleep cycle. Therefore, it’s often used as a sleep aid to combat issues like insomnia.

Sleep problems of potential users:​​​​​​​

• Difficulties falling asleep
• Light or unrestful sleep
• Short sleep duration (early awakening)
• Frequent awakenings
• Along with the difficulty or inability to fall back to sleep again
• Night shift workers
• Travellers into different time zone (jet lag)

Key Ingredients

Vitamins B1 and B6

Vitamins B contribute to the normal functioning of the nervous system and to normal mental activity. Also are necessary for the metabolism of proteins, glycogen and energy metabolism.

Vitamin B12

helps with fatigue, disorientation, memory loss, anaemia and damage to neural system. All of these difficulties can begin by low intake of B12. As it normally occurs in fish meat, eggs and milk, vegetarians and vegans, especially, should make sure they have a good uptake of this vitamin for maintaining proper brain function and blood flow.

Vitamin B2

Vitamin Β2 (riboflavin) helps to the maintenance of normal mucous membranes and red blood cells and the normal metabolism of iron, protects cells from oxidative stress and maintains eyesight and skin condition.

Melatonin

Melatonin is an indoleamine neurohormone whose levels vary in a daily cycle, thereby allowing the entrainment of the circadian rhythms of several biological functions in animals, plants, and microbes. Many biological effects of melatonin are transduced through melatonin receptors, including the MT1, MT2, and MT3 subtypes. Melatonin also acts as a powerful antioxidant that protects lipids, proteins, and DNA against oxidative damage. Glutathione peroxidase, superoxide dismutases, and catalase are upregulated by melatonin, and melatonin scavenges free radicals as a terminal antioxidant.

Magnolia officinalis extract

Magnolia officinalis is a traditional chinese medicine known for its neuroprotective and relaxing properties, being used to treat depression and anxiety as well as acting as a slight sedative. Modern research shows that it's helpful when treating various conditions like stress-induced anxiety and sleep troubles among others.

Summary of our scientific study
Increase of absorption of melatonin

Within the framework of research and development cooperation with Biocev, 100% solubility and cellular 600x higher absorption of melatonin, released from orally dissolving tablets for rapid onset of sleep, was achieved.

In humans, 90% of oral melatonin is already degraded during the first passage of the liver, thereby significantly reducing the effectiveness of the administered dose. 4quick sleep  prevents this undesirable degradation by a sophisticated process that involves the formation of the inclusion complex with melatonin and utilization of orally dissolving tablets as a dosage form.

One of the problems associated with the use of melatonin is its insufficient solubility. This can be increased by the formation of complexes with a suitable substance. Upon subsequent contact with body fluid, melatonin is released from this complex.

Do not hesitate to contact us for more information on the study!

Leaflet_4quick sleep mceODT 

Comparison of release of melatonin of 4quick sleep ​​​​​​​ (Neo Sleep Supplement) and commercial products:

Novel melatonin formulation ensures higher absorption in comparison to classic products up to 600 % and increases solubility of melatonin up to 100 %.

Most of the melatonin is released in the first 30 seconds after administration, in contrast with slow and poor release in other products.

Summary of our study